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  • Notch Signaling Overview 

  • Notch Receptors and Ligands

  • Notch Transcription Complex on HES1 DNA

  • Notch Negative Regulatory Region

The long-term goal of our research program is to understand the molecular logic of cell-surface receptors, focusing on proteins implicated in human disease. The laboratory currently emphasizes structure-function studies in Notch signaling.